THE ANTIVIRAL POTENTIAL OF ADIPORON, AN ADIPONECTIN RECEPTOR AGONIST, REVEALS THE ABILITY OF ZIKA VIRUS TO DEREGULATE ADIPONECTIN RECEPTOR EXPRESSION

Zika virus (ZIKV) is a pathogenic member of the flavivirus family, with several unique characteristics.Unlike any other arbovirus, ZIKV can be transmitted sexually and maternally, and thus produce congenital syndromes (CZS) due to its neurotropism.This challenges the search for safe active molecules that can protect pregnant women and their fetuses

A 48-year-old female presented to oncology clinic with a 2-month history of progressively worsening dull aching pain and swelling in the right flank along the inferior costal margin.Skin examination showed raised, erythematous lesion which was tender with induration and palpable subcutaneous nodules (Figure 1a).15 months prior, the patient was note

Metamorphosis in the insect larva is associated with disintegration, Non-Structural Heatsinks engulf and digestion of larval tissues.These processes are accompanied by a significant shift in physiological parameters like high activity of hydrolytic enzymes and decrease of pH.In the way, the metamorphosing larva resembles the processes occurring in

The in-box LOCA (Loss of Coolant Accident) represents a major safety concern to be addressed in the design of the WCLL-BB (water-cooled lead-lithium breeding blanket).Research activities are ongoing to master the phenomena and processes that occur during the postulated accident, to enhance the predictive capability and reliability of numerical tool